Posted: 20/10/2009
The biopharmaceutical contract manufacturing (CMO) industry has experienced a significant improvement in the average expression levels for both mammalian cell culture and microbial fermentation, according to the “Biopharmaceutical Contract Manufacturing 2009: Expanding Markets, New Capacities and Improved Performance” report recently published by HighTech Business Decisions.
The industry study with directors from 29 biopharmaceutical CMOs and 48 pharmaceutical and biotechnology companies showed that expression yield has improved significantly over the last two years. Firms attribute much of the increase to use of high-expression systems and continuous process improvement.